Torrey Pines Institute’s Associate Member, Predrag Cudic, Ph.D. has been awarded a grant for over $1.3 million from the Department of Defense (DoD) office of the Congressionally Directed Medical Research Programs (CDMRP). This grant will fund research to study “Novel Cyclic Lipopeptides for Treating Complicated Wound Infections.” The $1.4 M grant awarded to Torrey Pines Institute for Molecular Studies is part of a larger $2 M grant award. The total grant award is in support of a multi-principal investigator research study involving Dr. Robert Christy at the United States Army Institute of Surgical Research and Dr. Stephen Davis at the University of Miami School of Medicine. This scientific team is working together to develop a new class of antibacterial agents for the prevention and treatment of complicated combat-related or trauma-induced wound infections caused by multidrug-resistant pathogens.
Dr. Cudic, an organic chemist, with expertise in bioorganic chemistry will be studying a worldwide public health problem that has resulted from the alarming spread of multi-drug resistant bacteria combined with the frequent occurrence of biofilm-type infections, creating a growing need for new therapies. The continuing rise of antibiotic-resistant bacteria poses a serious threat to public health. According to the Centers for Disease Control and Prevention, virtually all important bacterial pathogens are becoming resistant to currently available antibiotics. Therefore, developing new antibiotics capable of treating infections from multi-drug resistant microorganisms is of vital importance.